IGHG3 and osteoporosis-pseudoglioma syndrome: The ROC analyses for distinguishing between melioidosis cases and healthy controls demonstrated AUROCCs of 0.87, 0.76, 0.83 and 0.58 for IgG1, IgG2, IgG3, IgG4 antibodies against Hcp1, respectively (Fig. 2c) and of 0.86, 0.95, 0.80 and 0.72 for IgG1, IgG2, IgG3, IgG4 antibodies against OPS, respectively (Fig. 2d).