CXCR2 and cancer: If blocking CXCL5’s receptor CXCR2 is detrimental to the proliferative state of the cancer cells in dead bone cultures, then blocking CXCR2 with the selective non-peptide CXCR2 antagonist SB225002 (antCXCR2) should attenuate CXCL5 activity by inhibiting CXCR2 and reduce cancer cell proliferation.