Meanwhile, we also observed that miR-574-5p targets (IBA57-AS1, KLRC2) was clearly downregulated, while miR-574-3p targets (S100A1 and TMEM54) was upregulated in these patients, which is in contrast to the corresponding miRNA change, suggesting the potential miRNA decay might be induced by these targets in gastric cancer patients (Fig. 5f). This evidence concerns the gene IBA57 and gastric cancer.