ACVR1B and gastric cancer: Moreover, expression of miR-574-5p/-3p sponges increased the luciferase reporter activity of miR-574-5p/-3p’s canonical targets, QKI6 and ACVR1B, respectively, in 293T cells (Fig. 4h), as well as increased their RNA and protein levels in two GC cell lines (Fig. 4i, Supplementary Fig. 3G).