SH3BGRL3 and cancer: In addition, GEPIA webtools (http://gepia.cancer-pku.cn/), Kaplan–Meier overall survival (OS) analysis and disease free survival (DFS) analysis indicated that KIRC patients with the higher level of TIP-B1 had dramatically shorter OS (Figure 1D) and DFS (Figure 1E) than those with the lower level of TIP-B1, which indicated TIP-B1 might paly central role in KIRC progression.