Rett Syndrome is a childhood neurologic disorder that affects 1 in 10,000 girls and is caused by mutations in a gene known as MECP2 (Rett, 1966; Hagberg et al., 1983; Lewis et al., 1992; Amir et al., 1999; Neul et al., 2010). The gene discussed is MECP2; the disease is atypical Rett syndrome.