DRD4 and glioblastoma: Having predicted the anti-DRD potential of LCC-09 and established the complicity of DRD4 expression and/or activity in the GSC-phenotype of GBM cells, we provided evidence that LCC-09 suppresses the viability and metastatic phenotype of GBM cells by dysregulating DRD4-mediated AKT/mTOR signaling (Figure 3).