To investigate the temporal localization of MAPK-regulated transcription factors in response to JCPyV infection, SVG-A cells were infected with JCPyV or mock infected then fixed and stained for both the viral early gene product TAg and a host-cell transcription factor target identified in the MAPK array: cMyc, SMAD4, or cJun. The gene discussed is MYC; the disease is infection.