AKT1 and small cell lung carcinoma: Regarding the improvement of the liver-renal function in SCLC patients, AC mycelia have been reported to lower oxidative stress associated with reducing the expression of cleaved caspase −3, −8, and −9, and the levels of phosphor-protein kinase B (Akt) and phosphor-nuclear factor-κB (NF-κB) in the liver [28].