Comparison of the Chow and HFD groups with regard to the levels of blood glucose, sizes of the kidneys and glomerulus (Fig. 1), and levels of 8‐OHdG (Fig. 2), GPX1 (Fig. 2), F4/80 (Fig. 3), and OPA1 (Fig. 4) indicated the successful development of NASH‐related kidney diseases. Here, OPA1 is linked to metabolic dysfunction-associated steatohepatitis.