Finally, as shown in Figure 5E, P3 tumours showed a marked decrease in the expression of proteins related to the spliceosome, such as the serine/arginine‐rich splicing factor 3 (SRSF3), survival of motor neuron‐related‐splicing factor 30 (SMNDC1), serine/arginine‐rich splicing factor 1 (SRSF1) and crooked neck‐like protein 1 (CRNKL1). This evidence concerns the gene SRSF3 and neoplasm.