HNF4A and neoplasm: β‐Catenin, as an important molecule in canonical Wnt signalling, interacts with T‐cell factor (TCF) or lymphoid enhancer factor (LEF) transcription factors in nucleus to induce cellular adhesion, tissue morphogenesis and development of tumour.53, 54 Our previous research demonstrated that E2 could activate β‐catenin signalling and increase the invasiveness of endometrial stromal cells (HECSs).27 Our present findings indicated that E2 could also increase dephosphorylated β‐catenin expression and nuclear translocation in EECs.