SERPINC1 and type 2 diabetes mellitus: As shown in Fig 2, the activity of PC [42.22 U/ml (33.69–44.33) vs 36.21 U/ml (33.0–40.19) respectively, p = 0.01] (Fig 2A), PS [235.94 U/ml (206.11–279.71) vs 211.67 U/ml (195.68–213.03) respectively, p<0.0001] (Fig 2B) and AT III [176.01 U/ml (145.0–211.47) vs 160.09 U/ml (140.99–178.04) respectively, p = 0.03] (Fig 2C) were significantly elevated in patients with well-managed T2DM compared to patients with poorly-managed T2DM (Fig 2).