We found that the levels and activity of PC, PS and AT III were significantly increased in T2DM patients who were on statins compared to patients who were statin-naïve; supporting the disposition that statins not only exert direct effects on lipids, but also influences coagulation, reducing the risk of thrombotic events among T2DM patients [38, 39]. The gene discussed is SERPINC1; the disease is type 2 diabetes mellitus.