In lung adenocarcinoma cells, Ha et al demonstrated that YB1 could promote the EMT mediated by transforming growth factor beta 1 (TGF‐β1) and promote the invasion and metastasis of cancer cells.34 What's more, it was validated that YB1 expression was higher in NPC specimens, negatively related to membrane E‐cadherin levels, but positively related to vimentin expression and associated with T stage and metastasis.35 These results mentioned were consistent with our findings. This evidence concerns the gene YBX1 and nasopharyngeal carcinoma.