TEAD4 and neoplasm: Activated YAP1 accumulates in the nucleus and induces a transcriptional programme critical for cell proliferation, migration and invasion by binding to TEAD4.43, 44 The Hippo pathway is composed of a kinase cascade, and the transcriptional coactivator YAP1 is up‐regulated in most human tumours.45, 46, 47 Therefore, the Hippo‐YAP1 signalling pathway and TEADs are potential targets for cancer therapy.48, 49, 50