Activated YAP1 accumulates in the nucleus and induces a transcriptional programme critical for cell proliferation, migration and invasion by binding to TEAD4.43, 44 The Hippo pathway is composed of a kinase cascade, and the transcriptional coactivator YAP1 is up‐regulated in most human tumours.45, 46, 47 Therefore, the Hippo‐YAP1 signalling pathway and TEADs are potential targets for cancer therapy.48, 49, 50. This evidence concerns the gene TEAD4 and cancer.