The results revealed that LPS i.t. induced more lung inflammation and injury in cKO mice than those of WT mice as previously reported.3 Though Res can effectively suppress the severity of ALI and lung inflammation in WT mice, myeloid cell‐restricted lack of SOCS3 prevented the suppressive effects of Res on cKO mice with ALI (Figure 5A‐B). Here, SOCS3 is linked to acute respiratory distress syndrome.