Several key conclusions were established from our biochemical analysis:Primary 1O2 generated by long-lived species, resultant from CAP treatment of medium, is sufficient to trigger the onset of efficient apoptosis induction in tumor cells, provided there is a sustained generation of secondary 1O2 (driven by tumor cell NOX1 and NOS) following the original primary 1O2 trigger. Here, NOX1 is linked to neoplasm.