CALR and cancer: We have focused on endoplasmic reticulum (ER) stress, autophagy,13–15 calreticulin (CRT) transfer from the lumen of the ER to the surface of the cancer cell and the release of ATP by the dying cancer cell16–19 and, consequent to these events, we have assessed dendritic cell (DC) activation, and found that the stated requirements for ICD induction were met.