RXRG and breast carcinoma: Expression analysis for RXRG mRNA using Breast Cancer Gene-Expression Miner v4.0 showed that high RXRG expression was associated with older age at diagnosis (n = 3600; Supplementary Fig. 3a; p = 0.0082), lower histological tumour grade (n = 3518; p = 0.0024; Supplementary Fig. 3b), ER-positive status (n = 5558; Supplementary Fig. 3c; p = 0.029).