Interestingly, while FACS analysis of the infiltrating immune cells revealed no significant differences in infiltration of total myeloid cells (CD11b+), macrophages (CD11b+F480+), or T cells (CD3+) (Supplementary Fig. 4d–h), there was a significant reduction in recruitment of CD11b+Gr1+ myeloid cells into tumours co-injected with Nlrp3−/− NMFs as compared with WT fibroblasts (Fig. 4d). The gene discussed is ITGAM; the disease is neoplasm.