OXT and Anxiety: In line with oxytocin’s assumed anxiolytic effects, oxytocin administration (1) increased the temporal stability of neural resting networks, (2) decreased the usage and presence of autonomic processing-related microstate C in favor of attention-related microstate D, and (3) decreased communication between the visual-processing related network microstate B and autonomic processing-related microstate C. Anxiety-related traits moderated these changes, with stronger changes in those participants with high rather than low anxiety levels, providing further evidence of oxytocin’s anxiolytic effects.