SAT1 and neoplasm: Interestingly, one of the genes that comprise the Stearman tumor field effect signature is the enzyme SAT1, which as expected is also up-regulated in the differentiated, immunosuppressive monocytes that are abundant in the disease cohort (\documentclass[12pt]{minimal}\usepackage{amsmath}\usepackage{wasysym}\usepackage{amsfonts}\usepackage{amssymb}\usepackage{amsbsy}\usepackage{mathrsfs}\usepackage{upgreek}\setlength{\oddsidemargin}{-69pt}\begin{document}$$p < 1.0\times 1{0}^{-8}$$\end{document}p<1.0×10−8, Wilcoxon rank-sums test, Fig. 3c).