LINC00645 and central nervous system cancer: To further evaluate the inhibitory effect of sh-linc00645 on glioma development in nude mice, the survival time of each group (n = 7 per group) was evaluated by Kaplan–Meier curves, and the sh-linc00645-treated group exhibited a significant improvement in survival compared with the control group (P < 0.05; Fig. 8f).