Importantly, however, when we compared phagocytic uptake of bacteria by the WT and TLR2 knockout cells after 45 min of infection, no differences were observed (Fig. 7B), confirming that the absence of TLR2 signaling does not impair phagocytosis of S. aureus by the THP-1 cells; however, it appears that S. aureus engages TLR2 signaling in these cells to facilitate its intracellular survival. This evidence concerns the gene TLR2 and infection.