Antiphospholipid syndrome (APS) is defined by the presence of arterial and venous thromboses and pregnancy morbidity (miscarriages, fetal deaths, premature births), in the company of antiphospholipid antibodies (aPL); namely, lupus anticoagulant (LA), anticardiolipin antibodies (aCL), or anti-β2 glycoprotein-I (anti-β2GPI) antibodies. This evidence concerns the gene APOH and autoimmune polyendocrinopathy.