CD4 and systemic lupus erythematosus: Wu, H.Y.; Quintana, F.J.; Weiner, H.L. Nasal anti-CD3 antibody ameliorates lupus by inducing an IL-10-secreting CD4+ CD25- LAP+ regulatory T cell and is associated with down-regulation of IL-17+ CD4+ ICOS+ CXCR5+ follicular helper T cells.