CDH3 and cancer: The ability of PF-06671008 to support redirected T cell killing and cytokine release in the presence of human PBMCs was performed using two cancer cell lines, which were confirmed by flow cytometry (Figure 2A) to express a different levels of cell surface P-cadherin (DU145, 231,000 copies/cell, and HCT-116, 114,000 copies/cell).