GNRHR and cancer: The highest level of GnRH-R was obtained for MDA-MB-231 and A2780 cells, with 5.7- and 5.6-fold higher surface expression, followed by U87MG, 4T1, and PANC-1 cell lines with around four-fold higher expression than MRC-5 cells, while HT-29 cancer cell line showed two-fold higher level of GnRH-R expression.