AKT1 and B-cell non-Hodgkin lymphoma: Given that genetic and pharmacological activation of FOXO1 induce apoptosis in different B cell lymphomas [13,16,17,18], we overexpressed an AKT-resistant inducible version of FOXO1 (FOXO1(3A)ER) (Figure 7A) in BL-41 and Namalwa BL cell lines.