CASP12 and melanoma: We then analyzed the overall survival of patients in the GSE98394 datasets and stratified them into high-level and low-level groups according to the median expression of these 13 candidate genes for screening prognostic genes, and found that the low expression of the three genes STK26, KCNT2, and CASP12 was associated with poor prognosis of patients with primary melanoma (Figure 5A).