For instance, TUG1 promoted KIAA1199 expression via miR‐600 to accelerate cell metastasis and epithelial‐mesenchymal transition in colorectal cancer,23 while knockdown of TUG1 ameliorated atherosclerosis via up‐regulation of the miR‐133a target gene FGF1. 12 Understanding the precise molecular mechanism by which lncRNAs function would facilitate the development of lncRNA‐directed diagnostics and therapeutics for COPD. Here, FGF1 is linked to chronic obstructive pulmonary disease.