Overexpression of TUG1 has been shown to protect the mouse liver against cold‐induced injury by inhibiting apoptosis and inflammation,11 whereas TUG1 knockdown inhibits hyperlipidaemia, decreases inflammatory response and alleviates atherosclerotic lesions.12 COPD is primarily caused by CS‐induced chronic inflammation. This evidence concerns the gene TUG1 and chronic obstructive pulmonary disease.