TUG1 and chronic obstructive pulmonary disease: They play crucial roles in the regulation of gene expression.5 The rapid development of RNA genomics has highlighted the involvement of various lncRNAs in COPD, such as LISPR1 and ANRIL.6, 7 The lncRNA taurine‐up‐regulated gene 1 (TUG1), a ~7.1 kb highly conserved lncRNA, was originally identified in taurine‐treated retinal cells.