Identification of two microbiome sputum clusters in airways disease, Haemophilus‐high and Haemophilus‐low, at clinical stability is consistent with previous findings at exacerbations.16 The Haemophilus‐high cluster was associated with increased pro‐inflammatory mediators IL1β and TNFα in asthma and COPD. The gene discussed is IL1B; the disease is asthma.