The best cutoff values for PCT, ESR and CRP in predicting PAD were 0.45 (sensitivity of 70.8% and specificity of 71.7%), 61.5 (sensitivity of 83.3% and specificity of 52.0%) and 49 (sensitivity of 83.3% and specificity of 63.8%), respectively. The gene discussed is ESR1; the disease is peripheral arterial disease.