More than 75% of breast cancers in the United States are diagnosed in women aged over 50 (Smigal et al., 2006; Jemal et al., 2007), and 80% of age-related breast cancers are hormone-receptor expressing luminal subtypes, whereas the triple negative disease is enriched among younger women (Jenkins et al., 2014). This evidence concerns the gene NR4A1 and breast carcinoma.