In parallel with their study in melanoma bearing mice described above, Pica et al. first demonstrated that the combination of Tα1 with αβ-IFN restored NK cell activity in mice inoculated with LLC cells (17) and that prolonged combined treatment with Tα1 and αβ-IFN or IL-2 significantly reduced tumor growth (19). The gene discussed is TAAR1; the disease is neoplasm.