MSCs isolated from mouse lymphomas (L-MSCs) compared with bone marrow-derived MSCs (BM-MSCs) promoted tumor cell proliferation vigorously, which was related to release of CCL2 by L-MSCs, resulting in recruitment of immunosuppressive cells, such as F4/80+ macrophages, CD11b+Ly6G+ neutrophils, and CD11b+ Ly6C+ monocytes to lymphoid tissues (81). This evidence concerns the gene CCL2 and neoplasm.