Regarding patient outcome, the presence of Fn DNA in CRC fresh-frozen tissue was associated with shorter cancer-specific survival (69.9 vs. 82.2% at 5 years; log-rank p = 0.028; Figure 3A) and overall survival (63.5% vs. 76.5% at 5 years; log-rank p = 0.037; Figure 3B). Here, FN1 is linked to cancer.