In addition, mutations in a variety of genes have pathogenic roles in FECD, including ZEB1, COL8A2, SLC4A11, AGBL1, LOXHD1, TCF4, and FEN1 (Elhalis et al., 2010; Vedana et al., 2016). The gene discussed is LOXHD1; the disease is Fuchs endothelial corneal dystrophy.