IRGM and acquired polycythemia vera: To investigate the role of IFN-γ priming, host cell Irgm1/Irgm3 molecules, and cell type in regulating the presentation of PV associated parasite antigens by MHC-I, wild type (WT) and Irgm1/m3 deficient (Irgm1/m3−/−) bone marrow derived macrophages (BMMΦs) or bone marrow derived dendritic cells (BMDCs) were primed with IFN-γ, or left unprimed and then host cells were infected with RH or RH-OVA.