IL1B and systemic lupus erythematosus: Conversely, increased CD80 expression and decreased CD209 expression and high IL-1β and -6 levels in supernatants were noted in the MDM of patients with SLE that were differentiated with LMP-IC compared with those that were differentiated with MDM-Unstim cells (Figures 1C,D, 2A,B and Supplementary Figure 4).