Pseudohypoparathyroidism (PHP) is a rare endocrine disorder derived from the defective activation of the cAMP transduction pathway by the parathyroid hormone (PTH) secondary to molecular defects affecting the alpha subunit of the stimulatory G protein (Gsα), which is encoded by the GNAS gene (1). Here, GNAS is linked to pseudohypoparathyroidism type 1A.