Furthermore, several studies have reported elevated serum MFAP4 levels in allergic asthma, liver disease, and liver fibrosis (Wulf-Johansson et al., 2013; Pilecki et al., 2015) as well as the role of MFAP4 in inflammatory mechanisms in the lung (Schlosser et al., 2006). This evidence concerns the gene MFAP4 and allergic asthma.