CBLN1 and Parkinson disease: Cer acyl chain composition has been shown to shift toward shorter acyl chain lengths (C16–C20) in the anterior cingulate cortex in PD patients (Cheng et al., 2011; Abbott et al., 2014), while there is an increase in long-chain SM and Cer (C21-C24) in the visual cortex (Cheng et al., 2011).