Moreover, in agreement with previous reports, WT1 activity was significantly higher in ovarian serous25 and uterine sarcoma26; TWIST1, a central player in the EMT, had increased activity in ovarian serous27 and uterine serous cancers; YY1, which regulates various processes of development and differentiation and is involved in tumorigenesis of breast and ovarian cancer28, had increased activity in these cancers. This evidence concerns the gene WT1 and cancer.