Studies have demonstrated that miRNA-145 inhibits the expression of its targets, nucleoside X-type motif-1 (NUDT-1), c-Myc, eIF4e and CDK4, supporting a tumor suppressor function of miRNA-145 in lung cancer (Ricciuti et al., 2014; MacDonagh et al., 2015). This evidence concerns the gene NUDT1 and lung carcinoma.