The p-values for the regression coefficients of log10 AFP (p= 0.003, OR = 24.83, 95% CI: 2.90-212.72) and log10 miRNA-215 (p =0.001, OR = 0.05, 95% CI: 0.01-0.29) indicated that both biomarkers contributed significantly to assign patients to HCC group. Here, AFP is linked to hepatocellular carcinoma.