This was in agreement with Spadaro et al.; El-Assaly et al. and Awadallah et al. who reported a significant elevation in serum AFP in HCC group compared to cirrhosis patients and control group (Spadaro et al., 2005; El-Assaly et al., 2008; Awadallah et al., 2011). Here, AFP is linked to hepatocellular carcinoma.