Given these discrepancies between the pro-oncogenic and antitumor activity caused by the activation of the IL-18 and IL-1β proteins, the aim of this study was both to evaluate the changes in the mRNA expression of these interleukins in cervical tissue, and to identify the variations in profiles that could be linked to degrees of malignancy in cervical premalignant lesions and tumor progression. Here, IL18 is linked to neoplasm.