To determine the effective and tolerance dose of ACE and pyrogallol for in vivo anti tumour experiment, we treated the mice with different concentrations of ACE and pyrogallol (10, 20 and 40 mg/kg body weight) every 2 days and observed for changes in behaviours, mortality and histology of vital organs (heart, kidney, liver, lungs) for damage (Figure 1). The gene discussed is ACE; the disease is neoplasm.