Persistent infection in the latent phase (latent infection) was determined for HHV-6 in one RA patient only; for B19V, in three RA and four OA patients; for HHV-7, in eight RA and nine OA patients; and did not correlate with the clinical characteristics or levels of cytokines and chemokine receptors (CCR1 and CCR2). This evidence concerns the gene CCR2 and disease arising from reactivation of latent virus.