OXT and migraine disorder: Preclinical as well as human studies indicate that the neuropeptide oxytocin impacts pain perception and processing of both the trigemino-nociceptive (e.g., migraine) and the spino-nociceptive (neuropathic pain) systems [52,53,54,55,56,57,58,59,60,61,62,63,64,65,66,67,68].