TP53 and colorectal cancer: We observed that AIU2001 inhibited the growth of human NSCLC A549, H1299, and H460 cells and human colorectal cancer HCT116 p53+/+ and HCT116 p53-/- cells, as well as human FLT(ITD)-positive AML MV4-11 and Molm-13 cells (Figure 1C and Supplementary Figure S1A–C).